Research and Development

Recent Research Publications by ULHT Staff

If you have published any articles/books/abstracts or given any conference presentations within the Trust, please send us publication details for publishing on R & D website.

Send your publication details to:

Fiona Smith
Research Governance Administrator
Lincolnshire Clinical Research Facility
Lincoln County Hospital
Greetwell Road
Lincoln LN2 5QY
Telephone: (01522) 512512 Ext.2915
E-mail: fiona.smith@ulh.nhs.uk

Bako Abdulmalik
O&G
Tension vaginal Tape (TVT). 9th Congress of the European Society of Gynecology. Sept 8 – 11, 2011. Copenhagen, Denmark
Bako Abdulmalik
O&G
V. V. Toh & V. Bogne & A. Bako. Management of recurrent vault prolapse. Int Urogynecol J (2012) 23:29–34
Steve Bailey
Maxillofacial Prosthetist
Presentation - A New Patient Consultation for a Patient with a Maxillary Defect. he Institute of Maxillofacial Prosthetists and Technologists 25th Scientific Congress 7-9 September 2011
Nick Dudley Dall, B., Dudley, N., Hanson, M., Moore, S. Seddon, D. Thompson, W. Verma, P. Guidance Notes for the Acquisition and Testing of Ultrasound Scanners for use in the NHS Breast Screening Programme. NHS BSP Publication No 70. NHS Cancer Screening Programmes, Sheffield 2011
Professor Eremin
Director of R & D
Manuscript - Samphao S, Eremin JM, El-Sheemy M, Eremin O. Management of the axilla in women with breast cancer: current clinical practice and a new selective targeted approach. (Review)Ann Surg Oncol. May;15(5):1282-96. 2008
Professor Eremin
Director of R & D
Manuscript - Satthaporn S, Aloysius MM, Robins RA, Verma C, Chuthapisith S, McKechnie A, El-Sheemy M. Vassanasiri W, Valerio D, Clark D. Jibril JA, Eremin O. Ex-vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha. BMC Immunology; 9: 32. 2008
Professor Eremin
Director of R & D
Manuscript Chuthapisith S, Eremin JM, Eremin O. Predicting response to neoadjuvant chemotherapy in breast cancer: molecular imaging, systemic biomarkers and the cancer metabolome (Review). Oncol Rep.Oct;20(4):699-703. 2008
Professor Eremin
Director of R & D
Manuscript - Boontham P, Robins A, Chandran P, Pritchard D, Cámara M, Williams P, Chuthapisith S, McKechnie A, Rowlands BJ, Eremin O. Significant immunomodulatory effects of Pseudomonas aeruginosa quorum-sensing signal molecules: possible link in human sepsis. Clin Sci (Lond). Dec;115(11):343-51. 2008
Professor Eremin
Director of R & D
Manuscript - Aloysius MM, McKechnie AJ, Robins RA, Verma C, Eremin JM, Farzaneh F, Habib NA, Bhalla J, Hardwick NR, Satthaporn S et al : Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs. J Transl Med, 7: 18 - 2009
Professor Eremin
Director of R & D
Manuscript - Aloysius MM, Robins, AR, Verma, Chandan, Eremin O. Targeting Human Telomerase Reverse Transcriptase: A Promising Anticancer Immunotherapeutic Approach. Cancer & Chemotherapy Rev. 2008, 3:35-43 2009
Professor Eremin
Director of R & D
Manuscript - Chuthapisith S, Eremin J, El-Sheemey M, Eremin O. .Breast cancer chemoresistance: Emerging importance of cancer stem cells. Surg Oncol. 19: 27-32. 2009
Professor Eremin
Director of R & D
Manuscript - Samphao S, Eremin JM, El-Sheemy M, Eremin O. Treatment of established breast cancer in post-menopausal women: role of aromatase inhibitors. (Review) Surgeon. Feb;7(1):42-55. 2009
Professor Eremin
Director of R & D
Manuscript - Eremin O, Walker MB, Simpson E, Heys SD, Ah-See AK, Hutcheon AW, Ogston KN, Sarkar TK, Segar A, Walker LG. Immuno-modulatory effects of relaxation training and guided imagery in women with locally advanced breast cancer undergoing multimodality therapy: a randomised controlled trial. Breast. Feb;18(1):17-25. 2009
Professor Eremin
Director of R & D
Manuscript - Samphao S, Eremin O. Ann Surg Oncol In reply: In favor of axillary lymph node dissection: need for a pragmatic view. Ann Surg Oncol. Apr;16(4):1066-7. 2009
Professor Eremin
Director of R & D
Manuscript - Chuthapisith S, Bean BE, Cowley G, Eremin JM, Samphao S, Layfield R, Kerr ID, Wiseman J, El-Sheemy M, Sreenivasan T, Eremin O. Annexins in human breast cancer: Possible predictors of pathological response to neoadjuvant chemotherapy. Eur J Cancer. May;45(7):1274-81.. 2009
Professor Eremin
Director of R & D
Manuscript - Tahara H, Sato M, Thurin M, Wang E, Butterfield LH, Disis ML, Fox BA, Lee PP, Khleif SN, Wigginton JM, Ambs S, Akutsu Y, Chaussabel D, Doki Y, Eremin O, Fridman WH, Hirohashi Y, Imai K, Jacobson J, Jinushi M, Kanamoto A, Kashani-Sabet M, Kato K, Kawakami Y, Kirkwood JM, Kleen TO, Lehmann PV, Liotta L, Lotze MT, Maio M, Malyguine A, Masucci G, Matsubara H, Mayrand-Chung S, Nakamura K, Nishikawa H, Palucka AK, Petricoin EF, Pos Z, Ribas A, Rivoltini L, Sato N, Shiku H, Slingluff CA, Streicher H, Stroncek DF, Takeuchi H, Toyota M, Wada H, Wu X, Wulfkuhle J, Yaguchi T, Zeskind B, Zhao Y, Zocca MB, Marincola FM. Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology. J Transl Med. Jun 17;7(1):45. 2009
Professor Eremin
Director of R & D
Manuscript - Samphao S, Eremin JM, Eremin O. Oncological emergencies: clinical importance and principles of management. Eur J Cancer Care, Nov, 19(6), 707-13, doi: 10,1111 fj, 1365-2354.2009.01091.x. 2010
Professor Eremin
Director of R & D
Manuscript - Sloan A, Hussain I, Maqsood M, Eremin O, El-Sheemy M. The effects of smoking on fracture healing. Surgeon. Apri, 8(2); 111-6; Epub 2010 Feb 4, Review. 2010
Professor Eremin
Director of R & D
Manuscript - Fisher CS, Cole DJ, Mitas M, Garrett-Meyer E, Metcalf JS, Gillanders WE, Mikhitarian K, Urist MM, Mann GB, Doherty G, Hermann VM, Hill AD, Eremin O, El-Sheemy M, Orr RK, Valle AA, Henderson MA, Dewitty RL, Sugg SL, Frykberg E, Yeh K, Bell RM, Baker MK. Molecular detection of micrometastatic breast cancer in histopathology – negative axillary lymph nodes fails to predict breast cancer recurrence: a final analysis of a prospective multi-institutional cohort study. Ann Surg Oncol. Oct 17 Suppl 3.312-20. Epub 2010 Sep 19. 2010
Professor Eremin
Director of R & D
Manuscript - Leslie G. Walker, Jennifer M. Eremin, Mark M. Aloysius, Wichai Vassanasiri,, Mary B. Walker, Mohamed El-Sheemy, Ged Cowley Jeanette Beer, Srila Samphao, Janice Wiseman, Jibril A. Jibril, David Valerio, David J. Clarke, Mujahid Kamal, Gerald W. Thorpe, Karin Baria, Oleg Eremin. Effects on quality of life, anti-cancer responses, breast conserving surgery and survival with neoadjuvant docetaxel: A randomised study of sequential weekly versus three-weekly docetaxel following neoadjuvant doxorubicin and cyclophosphamide in women with primary breast cancer. BMC, March 2011 (in press) 2010
Professor Eremin
Director of R & D
Book- Andrew Houghton and David Gray (eds), Symptoms and Signs in Clinical Medicine, 13th edition, Chamberlains Ch 16, Breast Chapter, O Eremin and J Eremin 2010
Professor Eremin
Director of R & D
Book - O. Eremin and H. Sewell (eds), Essential Immunology for Surgeons. Oxford Univ Press (Published March 2011).
  1. Chap 4 : Cancer and the immune response (M. Aloysius, L.G. Walker and O. Eremin)
  2. Chap 7 : Therapy and host defences (M. Aloysius, C. Verma and O. Eremin).
Jocelyn Fitzgerald Presentation: A Large NHS Trusts Experience of Implementing a Trust Wide Colorectal Enhanced Recovery Programme Across Multiple Sites - World Council Enterostomal Therapists UK Conference 2011,5 & 5 October 2011
Zoe Glossop
Trainee Clinical Scientist (Nuclear Medicine)
Presentation: MSc project (done at LCH), 'What impact do administered activity and collimator choice have on the achievability of the recommended count statistics in myocardial perfusion SPECT?' in the trainee sessions at EMPEC 2011 in Dublin.
Howard Glen Presentation: eDD - more than just a discharge letter: Improving the quality of discharge information to GPs in a large, multi-site trust THE NHS CLINICAL INFORMATICS BEST PRACTICE MARKET PLACE, Waterside, Watershed, Bristol, 25th March 2010
Dr Andrew R. Houghton Original Article: Kanagala P, Baker S, Green L, Houghton AR (2010) Functionally uni-leaflet mitral valves in a family: a case series. European Journal of Echocardiography 11(7): E27.
Dr Andrew R. Houghton Original Article: Kanagala P, Green L, Houghton AR (2010) Tetralogy of Fallot in a 26 year old. Journal of the British Society of Echocardiography 69: 23-24.
Dr Andrew R. Houghton Original Article: Shah NC, Hamilton L, Baker S, Houghton AR (2010) Though rare, fatal neurological complications can occur due to air embolism during agitated saline contrast echocardiogram. Journal of the British Society of Echocardiography 69: 24-26.
Dr Andrew R. Houghton Original Article: Kanagala P, Houghton AR (2010) Right heart thrombus-in-transit detected by transthoracic echocardiography: case report and literature review. Journal of the British Society of Echocardiography 70: 24-26.
Dr Andrew R. Houghton Original Article: Mercer C (2010) An interesting ambulatory ECG result. Journal of the Society for Cardiological Science and Technology 1(3): 4.
Dr Andrew R. Houghton Textbook: Houghton AR, Gray D (eds). 2010. Chamberlain's symptoms and signs in clinical medicine: an introduction to medical diagnosis. Hodder Arnold, London.
Christopher Knapp
Consultant Ophthalmologist
Original Article - Knapp CM, Gottlob I, McLean RJ, Rajabally YA, Abbott RJ, Rafelt S, Proudlock FA. Vertical Optokinetic Nystagmus in Parkinson's Disease Movement Disorders. 2009 Jul 30;24(10):1533-8.
Christopher Knapp
Consultant Ophthalmologist
Original Article - Knapp CM, Gottlob I, McLean RJ, Rafelt S, Proudlock FA. Effect of Distance upon Horizontal and Vertical Look and Stare OKN. J Vision 2009 Nov 30: 9(12): 23. 1-9
Christopher Knapp
Consultant Ophthalmologist
Poster - Knapp CM. Posterior Capsule Staining With Tryptan Blue During Cataract Surgery in Patients With a Peripheral Iridotomy presented at the Association for Research in Vision and Ophthalmology (ARVO), Fort Lauderdale, Florida, USA May 6th, 2010
Christopher Knapp
Consultant Ophthalmologist
Book Chapter - Knapp CM, Ram V, Brown L, Sampath R. Chapter 9: Orbital Lymphoma. Surgical Atlas of Orbital Surgery, edited by Subrahmanyam Mallajosyula. Published by McGraw-Hill Medical 2009.
Christopher Knapp
Consultant Ophthalmologist
Book Chapter - Knapp CM, Ram V, Brown L, Sampath R. Chapter 11: Orbital Tumours of Neurological Origin. Surgical Atlas of Orbital Surgery, edited by Subrahmanyam Mallajosyula. Published by McGraw-Hill Medical 2009.
Christopher Knapp
Consultant Ophthalmologist
Guest Speaker - ‘Neurological Ptosis’ and ‘Optic Nerve Tumours’ presented to the Oculoplastics Association of India (OPAI) meeting, Mumbai, India, 20th & 21st November 2010 Regards
Bethan Myers
Haematology Consultant
Bleeding and thrombotic complications of kidney disease - Blood reviews - Elsevier
Bethan Myers
Haematology Consultant
Comparative efficacy and safety of intravenous ferric carboxymaltose (Ferinject) and iron(III) hydroxide dextran (Cosmofer) in pregnancy – Obstetric Medicine 2012 – currently in print
Bethan Myers
Haematology Consultant
Review Heritable thrombophilias: implications for pregnancy and current evidence for treatment - The Obstetrician & Gynaecologist - 2011;13:225–230
Bethan Myers
Haematology Consultant
Review Diagnosis and management of antiphospholipid syndrome in pregnancy - The Obstetrician & Gynaecologist - 2011;13:15–21
Bethan Myers
Haematology Consultant
Antiphospholipid syndrome
Bethan Myers
Haematology Consultant
Diagnosis and management of Thrombocytopenia in pregnancy - Fetal and Maternal Medicine Review 2011; 22:2 144–167
Professor Senaka Rajapakse
Consultant Physician - EAU
Rodrigo C, Sheriff R, Rajapakse S, Lanerolle RD, Sheriff MHR. A two-year retrospective analysis of renal transplant patients in Sri Lanka. Saudi Journal of Kidney Diseases and Transplantation 2011;22(1):174-8.
Professor Senaka Rajapakse
Consultant Physician - EAU
Rajapakse A, Rajapakse S, Sharma JC. Is investigating for carotid artery disease warranted in non-cortical lacunar infarction? Stroke 2011;42(1):217-20
Professor Senaka Rajapakse
Consultant Physician - EAU
Rajapakse S, Rodrigo C, Fernando SD. Drug treatment of scrub typhus. Tropical Doctor 2011; 41(1):1-4.
Professor Senaka Rajapakse
Consultant Physician - EAU
Fernando SD, Rodrigo C, Rajapakse S. Current evidence on the use of antifilarial agents in the management of Bancroftian filariasis. Journal of Tropical Medicine 2011;2011:175941
Professor Senaka Rajapakse
Consultant Physician - EAU
Rodrigo C, Gamakaranage CSSK, Epa DS, Gnanathasan A, Rajapakse S. Hypothyroidism with two rare life threatening complications; acute kidney injury and paralytic ileus. Thyroid Research 2011;4(1):7
Professor Senaka Rajapakse
Consultant Physician - EAU
Fernando SD, Rodrigo C, Rajapakse S. Chemoprophylaxis in malaria: drugs, evidence of efficacy and costs. Asian Pacific Journal of Tropical Medicine 2011;4:330-336
Professor Senaka Rajapakse
Consultant Physician - EAU
Ranasinghe P, Perera YS, Lamabadusuriya DA, Kulatunga S, Jayawardana N, Rajapakse S, Katulanda P. Work-related complaints of arm, neck and shoulder among computer office workers in an Asian country: prevalence and validation of a risk-factor questionnaire. BMC Musculoskeletal Disorders. 2011;12(1):68.
Professor Senaka Rajapakse
Consultant Physician - EAU
Gamakaranage CS, Rodrigo C, Jayasinghe S, Rajapakse S. Hypokalemic paralysis associated with cystic disease of the kidney: case report. BMC Nephrology. 2011;12(1):16.
Professor Senaka Rajapakse
Consultant Physician - EAU
Fernando JI, Rajapakse S, for the Critical Care Study Group, Sri Lanka. Current status of intensive care services in Sri Lanka: an observational study. International Journal of Critical Illness and Injury Science. In press. Accepted 1st July 2011.
Professor Senaka Rajapakse
Consultant Physician - EAU
Ranasinghe P, Perera YS, Lamabadusuriya DA, Kulatunga S, Jayawardana N, Rajapakse S, Katulanda P. Work related complaints of neck, shoulder and arm among computer office workers: a cross-s ectional evaluation of prevalence and risk factors in a developing country. Environmental Health 2011, 10:70
Professor Senaka Rajapakse
Consultant Physician - EAU
Navinan R, WIjayaratne DR, Rajapakse S. Final year medical students' perspectives regarding the curriculum in public health. Indian Journal of Community Medicine. 2011; 36:268-74
Professor Senaka Rajapakse
Consultant Physician - EAU
Gunaratna RI, Handunnetti S, Bulathsinghalage MRC, Somaratne P, Jayanaga A, De Silva HJ, Rajapakse S. Serum nitrite levels in Sri Lankan patients with Leptospirosis. Asian Pacific Journal of Tropical Medicine 2012; 5:75-8.
Professor Senaka Rajapakse
Consultant Physician - EAU
SD Fernando, Rodrigo C, Rajapakse S. Primaquine in vivax malaria: an update and review on management issues. Malaria Journal 2011;10(1):351
Ciro Rinaldi
Haematology Consultant
Book title: Hematology - Science and Practice (ISBN 979-953-307-516-6)
Chapter title: MOLECULAR MECHANISMS IN PHILADELPHIA NEGATIVE MYELOPROLIFERATIVE NEOPLASIA. Authors: Ciro Roberto Rinaldi, Ana Crisan and Paola Rinaldi
Ciro Rinaldi
Haematology Consultant
Preferential nuclear accumulation of JAK2V617F in CD34+ but not in granulocytic, megakaryocytic, or erythroid cells of patients with Philadelphia-negative myeloproliferative neoplasia. Rinaldi C et al. - Blood. 2010 Dec 23;116(26):6023-6. Epub 2010 Sep 22.
Helen Walker Presentation: Case Study: a multi-disciplinary team approach to managing abdominal complications due to severe diverticular disease – World Council Enterostomal Therapists UK Conference 2011,5 & 5 October 2011

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